Bronchoalveolar lavage from patients who developed severe pneumonia possessed a unique macrophage population that expressed high levels of inflammatory chemokines (CCL2, CCL3, CCL4, CXCL9, CXCL10, CXCL11) and ISGs (APOBEC3A, ISG15, ISG20, GBP1, GBP5, IFITM3, MX1), which are similarly upregulated in TB and HIV-TB patients [16]. The gene discussed is CXCL9; the disease is tuberculosis.