Additionally, because previous work has alluded to more efficient recycling of TrkB.T1 receptors back to the plasma membrane in PC12 cells and neurons33, we next wanted to identify the distribution of TrkB.T1 in normal human brain and human gliomas based on these DGCA results implicating endocytic and vesicular transport genes. The gene discussed is NTRK2; the disease is central nervous system cancer.