One KID syndrome has been noted to confer a predisposition to SCC.131 Approximately 11% of patients with KID syndrome develop this condition.132 Oculodentodigital dysplasia (ODDD) is another congenital disorder caused by a mutation in the GJα1 gene, which encodes Cx43.133 It is characterized by multiple phenotypic abnormalities involving the face, limbs, teeth and eyes, as well as neurological symptomatology. The gene discussed is GJA1; the disease is KID syndrome.