STING1 and cancer: In cancer-derived HeLa cells or HEp-2 human laryngeal carcinoma cells, STING was proposed to facilitate HSV-1 production via an unknown mechanism, whereas in human embryonic lung cells or HEK293T cells derived from normal tissues, STING reduces viral yields.112 Whether the virus adopts different regulation strategies towards STING in different cell types to achieve maximum colonisation is an interesting topic that remains to be explored.