STING1 and neoplasm: Tumour-derived exosomes have been suggested to deliver tumour DNA to nearby dendritic cells.146 The breakdown of the micronuclear membrane might represent a mechanism to transport tumour DNA into the exosomes.147 In addition, immune cells are also suggested to receive tumour-derived cGAMP through gap junctions or cGAMP transporters, therefore leading to the activation of STING signalling.81,82,148–150