Light microscopy, immunofluorescence and electron microscopy examinations showed that there were no significant difference in Ehrenreich-Churg stage, glomerular sclerosis (global sclerosis and segmental sclerosis), tubular atrophy, interstitial inflammatory cell infiltration, interstitial fibrosis, renal arteriolopathy, average GBMT, glomerulus antigen deposit for IgG (IgG1, IgG2, IgG3, and IgG4), IgA, IgM, C3, C1q, PLA2R and THSD7A between two groups (Table 2). Here, IGHG3 is linked to Glomerular sclerosis.