CRP and major depressive disorder: There was no significant difference in age distribution between the two groups (P > 0.05) (see Table 1)。The distribution strength of risk factors in ACS group was overweight (64.10%), hypertension (49.88%), hyperlipidemia (40.72%), diabetes (23.37%), depression or anxiety disorder (16.63%), gynecological diseases (16.39%), hyperuricemia (14.94%), family history of early-onset CHD (14.94%), high homocysteine (11.33%), low thyroid function (9.64%), high cholesterol (8.43%), high C - reactive protein (7.47%), and was significant difference compared between the two groups(P < 0.01).