Interestingly, a new study based on clinical data and next-generation sequencing (NGS) on a cohort of 1348 patients with a wide range of cancers presented the most frequent coalterations in the presence of GNA alterations (GNAS, GNAQ, and GNA11) to be in AURKA, SRC, CBL and LYN genes [48]. The gene discussed is GNAQ; the disease is cancer.