Using the N-NOSE mechanism, the animal experiment conducted on pancreatic cancer demonstrates that C. elegans can recognize the odor of pancreatic cancer in the urine of the oncogenic KrasG12D model, whereas the role of c-Met, a receptor of hepatocyte growth factor, was not detected [36], suggesting that the downstream products of KrasG12D may be involved in the alteration of the chemotaxis or olfactory behavior response in C. elegans. Here, HGF is linked to pancreatic neoplasm.