Taking into account our observation, our next studies ought to be focused on evaluating leptin and leptin-related pathways in both in vitro and in vivo models and assessing the influence of cisplatin in different endometrial cancer cell lines (EC-1-A, HEC-1-B corresponding to histological grade 2 (G2) and KLE corresponding to histological grade 3 (G3)). Here, LEP is linked to endometrial cancer.