DISC1 and schizophrenia: Furthermore, the possible association of ERBB4 with schizophrenia may also be elucidated through the Wnt/β-catenin pathway, a well-established key player in the neurodevelopmental mechanisms involved in schizophrenia [55]; this pathway in conjunction with signaling cascades of schizophrenia-risk genes, DISC1 and NRG, has been reported to converge with ERBB4 [56].