Salient features included the evidence that the only secreted member of this family, the primate‐specific APOL1, protects humans against the African parasite Trypanosoma brucei, whereas natural APOL1 C‐terminal variants termed G1 and G2, which also protect against the sleeping sickness agent Trypanosoma rhodesiense, can cause kidney disease [2, 3, 4]. This evidence concerns the gene APOL1 and human African trypanosomiasis.