In particular, it was significantly correlated with monocyte markers (CD86, CD115), TAM markers (CCL2, IL10), M1 macrophage markers (INOS, IRF5, COX2) and M2 macrophage markers (CD163, VSIG4, MS4A4A) in STAD (P < .0001; Figure 4A–H). Here, PTGS2 is linked to gastric adenocarcinoma.