Zhang et al. (2017) found a circRNA from UBAP2 gene to be the most upregulated circRNA in osteosarcoma patient samples respect to adjacent non-tumoral tissues. High expression of circUBAP2 correlated with lower overall survival of the patients, promoted osteosarcoma growth and inhibited apoptosis both in vitro and in vivo. This evidence concerns the gene UBAP2 and osteosarcoma.