In fact, the overwhelming majority of studies report the presence of α-SMA+ myofibroblasts in 33–81% of the keloids analyzed (Santucci et al., 2001; Kamath et al., 2002; Amadeu et al., 2003; Lee J. Y. Y. et al., 2004; Moshref and Mufti, 2009). Here, ACTA1 is linked to keloid.