Apart from its prognostic value, in comparison with normal tissue counterparts, the expression of Ran was found to be increased in breast, renal, gastric, colon, pancreatic, ovarian, and lung cancers (Azuma et al., 2004; Ouellet et al., 2005, 2006; Abe et al., 2008; Xia et al., 2008b; Yuen et al., 2012; Deng et al., 2014; Sheng et al., 2018). The gene discussed is RAN; the disease is lung cancer.