MiR-10b overexpression enhances cell migration and invasion by targeting HOXD10; while subexpression of miR-10b-3p, coded in the same miR-10b locus, participates in breast cancer onset by upregulating the cell cycle regulators BUB1, PLK1, and CCNA2 (53). The gene discussed is HOXD10; the disease is breast carcinoma.