More in detail, Harel et al. showed that a higher OXPHOS and lipid metabolism augment the antigen presentation of melanoma cells, through the increase of MHC proteins expression (HLA-A, HLA-C, and B2M which consist MHCI, and CD74, a chaperone of MHCII), of several factors involved in the antigen processing and presentation machinery (including TAP1 and TAP2 which are peptide antigen transporters, TAPBP which acts as a bridge between the MHC and the peptide transporters), and PSME1, a component of proteasome. Here, HLA-C is linked to melanoma.