Adhesion molecules (intracellular adhesion molecules-1, vascular cell adhesion molecules-1, and selectins), which were found to be overexpressed following PDT, can recruit neutrophils and other inflammatory cells to tumor sites and convert the tumor vascular endothelium from a non-thrombotic, non-adhesive barrier between blood and tumor tissue to a pro-adhesive surface permitting infiltration of blood constituents (60). The gene discussed is VCAM1; the disease is neoplasm.