After obtaining written informed consent, we performed array comparative genomic hybridization analysis and identified a de novo 2.76 Mb deletion (arr[GRCh37] 2q36.3q37.1(230377789_233136164)x1) encompassing 25 protein-coding genes; of these genes, TRIP12 and NPPC are known to affect phenotypes attributable to autosomal dominant inheritance and cause developmental delay and short stature with small hands, respectively. Here, NPPC is linked to Global developmental delay.