Different studies indicated that poor diabetes self-care management behavior, low adherence to medicine, a higher level of anxiety, depression, obesity, literacy status, alcohol and tobacco consumption, treatment strategy, patient's knowledge about disease and treatment, treatment noncompliance, exercise, diet, irregular insulin injection schedules, alcohol use, fear of hypoglycemia, finance, glucose monitoring are associated with poor glycemic control [[10], [11], [12], [13], [14], [15], [16], [17]]. This evidence concerns the gene INS and diabetes mellitus.