In order to establish the correlation between MDR1gene expression and genotype with chemotherapeutic response to infer a clinical significance for the management of ovarian cancer patients, we have genotyped a total of 52 clinical ovarian tumor tissues along with 19 control samples of healthy women in exon-12 (C1236T), 21- (G2677T/A) and exon-26 (C3435T) of MDR1 gene, respectively. This evidence concerns the gene ABCB1 and ovarian carcinoma.