CENPB and lung adenocarcinoma: Behnan et al. (2016) showed that the inhibition of CENPA expression in glioblastoma cells can reduce sphere-forming capacity, proliferation, and cell viability. In vitro experiments by Cheng et al. (2019) in mice confirmed that elevated FOXM1 expression enhanced CENPA and CENPB expression, which promoted cell cycle progression and cell proliferation, thereby promoting LUSC cell growth. Regarding prognosis, lung adenocarcinoma (LUAD) patients with high CENPA expression experience poor OS based on data integrated from six different GEO chips by Liu et al. (2018).