Interestingly, semen concentration of IP-10 steadily increased during the first month of infection and levels were not stabilized even in the chronic phase (Mann-Whitney test, p = 0.01, 0.003, 0.0005, 0.002, 0.02 and < 0.0001 for 10, 28, 29, 35, 160 and 315 dpi, respectively, Figure 1F), suggesting a role for IP-10 in lymphocytes trafficking to mucosal tissues during HIV/SIV infection. The gene discussed is CXCL10; the disease is infection.