The efficacy of apoptosis induction of the new constructs was tested in vitro in DU-145 cells, a human prostate cancer cell line that had served already as a model for scFv62-TRAIL, a construct using monomeric TRAIL (Hartung et al., 2011; Hartung and Pardo, 2016). This evidence concerns the gene TNFSF10 and Familial prostate cancer.