As an enzyme that also has transport functions and hydrolyzes ATP activity, we can easily associate the influential role played by members of the ABC protein superfamily in tumor multidrug resistance research, including ABCB1 (MDR1), ABCC1, ABCG, etc. Through bioinformatics analysis, we found that overexpression of OLA1 has been found for various types of cancer, including breast cancer, and may be connected with poor survival, (Zhang et al., 2009a; Zhang et al., 2009b; Sun et al., 2010; Bai et al., 2016; Ding et al., 2016; Huang et al., 2020). This evidence concerns the gene ABCB1 and cancer.