FBN2 encode the fibrillin 2 which has a crucial role in ocular morphogenesis in mice37 and is expressed in the corneal stroma but not in the corneal epithelium of mice heterozygous for the micropinna microphthalmia (Mp) mutation, a 660-kb inversion on chromosome 18 that disrupts the Fbn2 gene38,39. The gene discussed is FBN2; the disease is microphthalmia.