PTEN and lung adenocarcinoma: Similarly, in a recent study, PTEN was also reported as the target of miR-410, and human umbilical cord mesenchymal stem cell-derived extracellular vesicles increased the growth of lung adenocarcinoma (LUAD) cells by transferring miR-410 to cells and subsequently decreasing the protein level of PTEN.42 However, the study mainly focused on exploring the effects and mechanism of hUCMSCs on LUAD growth without addressing the functions of miR-410 in EMT, radioresistance or the PI3K/mTOR pathway in lung cancer.