ZEB1 and cancer: Studies showed that the expression of E-cadherin increased the radiosensitivity of breast cancer cells.48 Moreover, miR-205 inhibited DNA damage repair and acted as a radiosensitizer by targeting ZEB1 in breast cancer cells,49 whereas the promotion of DDR by ZEB1 might be the mechanism underlying the correlation between EMT and radioresistance.50 Hence, the roles of EMT-related markers and transcription factors in the radioresponse suggested that EMT might be one of the causes of radioresistance in cancers.