However, it has been described in patients with other infectious conditions, such as HBV, Nocardia, Pseudomonas, and Fusarium; non-infectious diseases, such as hypothyroidism, chronic lymphocytic leukemia, rheumatoid arthritis, and Crohn's disease; and possibly also as a medication-induced condition, since it has already been described during the treatment of psoriasis with etanercept, an inhibitor of the tumor necrosis factor (TNF)-α and in association with the use of propylthiouracil, with rapid resolution after is discontinuation.55 This evidence concerns the gene TNF and rheumatoid arthritis.