IL1B and colorectal cancer: He et al. have reported that IL-1B rs2853550 heterozygotes (OR = 0.34, 95% CI: 0.2–0.7, p = 0.0028) and the “A” allele are associated with a significantly reduced risk of colorectal cancer (OR = 0.43, 95% CI: 0.2–0.9, p = 0.0015) (He et al. 2011b).