FASLG and systemic lupus erythematosus: To conclude, the meta-analysis finds a consistent relationship between aPL and AHIA (IgM aCL > IgG aCL > LA > IgG aβ2GPI) as well as between AIHA and thrombosis, particularly in patients with SLE: while plausible thrombogenic pathways linking AIHA and SLE do exist, the intimate nature of the reaction between different aPL isotypes and erythrocyte structures remains unclear and warrants further research