FASLG and autoimmune polyendocrinopathy: Recurrent arterial or venous thrombosis and/or obstetric morbidity in the presence and persistence of antiphospholipid antibodies (aPL) detected via immunoassays or clotting tests characterise the antiphospholipid syndrome (APS): APS may be isolated (primary APS, PAPS) or associated with other autoimmune disease (secondary APS), the most common being represented by systemic lupus erythematosus (SLE, lupus-related APS) [1].