Ω-3 PUFAs enriched diet suppressed the growth of MC38 colorectal carcinoma in mice, and treatment of tumours with epoxydocosapentaenoic acids, metabolites of ω-3 PUFAs, reduced expressions of protooncogens C-myc, Axin2 and C-jun in tumour tissues [248]. This evidence concerns the gene JUN and neoplasm.