DHA inhibited proliferation and progression of A549 non-small cell lung cancer cells through ROS-mediated inactivation of the PI3K/Akt pathway [233], and also through the miR-138-5p/FOXC1 pathway in A549 and H1299 human lung cancer cell lines and LLC murine lung cancer cells [234]. The gene discussed is AKT1; the disease is lung carcinoma.