TP53 and colorectal carcinoma: Using combined PiCRUSt (via Nephele) and LEfSe analyses, it was shown that there were marked changes in microbial functions amongst the experimental groups particularly after treatment with resveratrol, which included those that were connected to CRC (e.g., P53 signaling) [50] and those involved in generation of Tregs (e.g., TGF-β signaling) [51] (Figure S7).