TRPA1 and asthma: Although increasing evidence suggests TRPA1 involvement in the pathogenesis of chronic obstructive pulmonary disease (COPD), asthma, chronic cough, cystic fibrosis etc., pointing to the important therapeutic potential of TRPA1 in the pharmacological treatment of chronic pulmonary diseases [26,46,54,57,58,59,60,61,62], there are few in vivo data concerning its function in airway inflammation.