For TET2 and SRSFP95H mutations, myeloid bias was associated with CHIP or the initiation of myelodysplastic/myeloproliferative syndrome, whereas for DNMT3A multipotent stem cell origin was described in the context of CHIP (Buscarlet et al., 2018; Smeets et al., 2018). Here, TET2 is linked to myelodysplastic/myeloproliferative neoplasm.