Alanine aminotransferase (ALT) is the most common biochemical indicator used to evaluate liver inflammation,9 and current guidelines for the prevention and treatment of hepatitis B10 suggested that chronic hepatitis B (CHB) patients with persistently normal alanine aminotransferase levels (PNALT), and the infection may develop into liver cirrhosis or cancer. The gene discussed is GPT; the disease is cirrhosis of liver.