The baseline characteristics, including age, sex, SBP, DBP, gross/microscopic hematuria, Scr, serum IgA/IgG/IgM, serum C3, 24-h proteinuria, eGFR, CrCl, BUN, treatment regimes, and histological characteristics, were demonstrated in Supplementary Table 2. The gene discussed is C3; the disease is Microscopic hematuria.