KLF11 and panic disorder: Thus, in the present study, we for the first time examined KLF11 DNA methylation levels in (1) patients with panic disorder in a case–control design taking into account comorbidity with MDD, and (2) in an independent sample of patients with MDD by comparing symptom subtypes (i.e., anxious vs. non-anxious depression) in an effort to for the first time explore the role of KLF11 on an epigenetic level in anxiety and affective disorders.