AURKB and oligospermia: It is reported that an Aurkb knockout mouse in which exons 2–6 were excised is embryonic lethal, older Aurkb heterozygous mice approximately 12–24 months of age show decreased survival due to susceptibility for tumorigenesis, and a fraction of Aurkb heterozygous males suffer from oligospermia by 12 months of age (Fernandez-Miranda et al., 2011).