The coverage of CD31-positive blood vessels by perivascular AQP4 was significantly increased in the perilesion/ipsilateral cortex WT stroke animals compared to sham (WT-Sham compared to WT-Ipsi: 95% CI [−73.27 to −1.223], p = 0.0384) (Figure 2E). Here, PECAM1 is linked to stroke disorder.