PRNCR1 and Familial prostate cancer: Many variants such as PRNCR1 (prostate cancer-associated non-coding RNA) are located in exon regions, for example, rs1456315 G/A; it has been predicted to affect the lincRNA secondary structure of PRNCR1 (Chung et al., 2011) and then alter lincRNA stability and conformation, even giving rise to the modification of its interacting partners.