Surprisingly, large-scale studies have revealed that several lincRNAs are transcribed from the chr8q24 locus, such as CCAT1 (Kim et al., 2014), CCAT2 (Ling et al., 2013), PVT1 (Hanson et al., 2007), PCAT1 (Guo et al., 2016), and PRNCR1 (Li et al., 2013); all of these encompass multiple cancer-associated variants. The gene discussed is CCAT2; the disease is cancer.