sGC stimulation can attenuate LV remodeling after myocardial infarction in mice (Frankenreiter et al., 2018; Berg et al., 2019), decrease extracellular matrix protein production in human cardiac fibroblasts following TGF-β stimulation, and attenuate vascular dysfunction in diabetic rats (Grontved et al., 2014). Here, TGFB1 is linked to myocardial infarction.