SC involvement in additional myopathies pathologies was reported for XL myotubular myopathy, SEPN1-related myopathies, and as a primary cause for EMARDD (early-onset myopathy with areflexia, respiratory distress, and dysphagia; Castets et al., 2011; Logan et al., 2011; Boyden et al., 2012; Lawlor et al., 2012; Di Gioia et al., 2017). This evidence concerns the gene SELENON and myopathy.