PRKN and Parkinson disease: Other PD associated genes have also been implicated in the autophagy and mitophagy pathways including GBA, VPS35, ATP13A2, PINK1, and Parkin (Ramirez et al., 2006; Vives-Bauza et al., 2010; Zavodszky et al., 2014; Fernandes et al., 2016; Taguchi et al., 2017).