APOC3 and idiopathic interstitial pneumonia: The pale blue line in Fig. 3 highlights the canonical pathways obtained with the uploaded proteins: starting from PDGFR, following the arrows, the signal transduction cascade modulates several transcription factors, such as PPAR-γ/RXR-alpha and PPAR-α/RXR-alpha, which in turn modulate APOC3, which proved to be abundant in serum of IPF patients after one year of nintedanib treatment.