When we measured SOD, catalases and GSH in brain tissue, we found that the concentrations of SOD (Fig. 8B and Supplementary Fig. 2B), catalase (Fig. 8E and Supplementary Fig. 2D), and GSH (Fig. 8F and Supplementary Fig. 2E) increased substantially after stroke with pamoic acid treatment. The gene discussed is SOD1; the disease is Stroke.