When we measured SOD, catalases and GSH in brain tissue, we found that the concentrations of SOD (Fig. 8B and Supplementary Fig. 2B), catalase (Fig. 8E and Supplementary Fig. 2D), and GSH (Fig. 8F and Supplementary Fig. 2E) increased substantially after stroke with pamoic acid treatment. This evidence concerns the gene SOD1 and stroke disorder.