SOD1 and cardiac rhythm disease: KD of several candidate factors (e.g., sala, BG642167) in oenocytes induced cardiac arrhythmia (Supplementary Fig. 3a), similar to the KD of Cat and Sod1. On the other hand, our genetic screening identified four candidates whose KD specifically in oenocytes significantly attenuated PQ-induced cardiac arrhythmicity (Fig. 2b).