Although some patients with cryptococcosis seemed to be immunocompetent, some immune gene characteristics such as mannose-binding lectin (MBL) polymorphisms, FCGR (Fc-gamma receptors FccRs coding genes) 2B 232I/T genotype, FccRIIB polymorphisms, specific immunological status and/or a particular lifestyle were associated with these individuals8–10,20. This evidence concerns the gene FCGR2A and cryptococcosis.