POLR3H and asthma: For example, a 20 bp eSTR was associated with nine eGenes (seven lead) connected via distal loops (Fig. 6e) and was in strong LD with a UKBB variant linked to 19 distinct traits including asthma and body fat percentage; two of the genes associated with this variant (TCF20 and POLR3H) have also been previously linked to autism26,27.