MYD88 and diffuse large B-cell lymphoma: Somatic mutations similar to the ABC (activated B cell)-type DLBCL have been observed by massive parallel sequencing [22,61]: mutations in the NFkB pathway such as the L265P MYD88 mutation (60–70% of the cases), TNFAIP3/A20, CD79B and CARD11 [62,63,64].