RIPK3 and adenocarcinoma: In subgroup analyses according to histology, CHIP(−)/RIPK3(+) was associated with shorter OS (HR 2.096, 95% CI 1.234–3.561, p = 0.006) and showed a trend toward shorter OS (HR 1.456, 95% CI 0.936–2.267, p = 0.096) in adenocarcinoma (Table S2).